Movement disorders

What are movement disorders?

Movement disorders are conditions that cause spasms, jerking or shaking. They may reduce or slow movement, and they can affect activities such as writing or playing the piano.

There are generally three types of movement disorders: excessive movement (hyperkinetic), abnormally reduced intentional movement (hypokinetic), and abnormal involuntary movement (dyskinesia).

Genetic conditions, traumatic injury, nervous system disease, infections, medication side effects, and other factors may cause a movement disorder.

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How are movement disorders diagnosed and evaluated?

Your doctor will take your medical history and perform a physical exam with a neurological assessment. This will include checking your motor skills and reflexes. You may need to walk a short distance so your doctor can look for any problems with the way you walk.

Your doctor may order more tests, including:

blood tests.
lumbar puncture to analyze the cerebrospinal fluid.
electromyography to measure the electrical impulses along nerves, nerve roots and muscle tissue.
electroencephalogram (EEG) to check the electrical activity of the brain.
electrocardiogram (ECG or EKG) to check the heart’s electrical activity and determine if heart problems are causing your disorder.
muscle biopsy to distinguish between nerve and muscle disorders.

Doctors often use imaging tests to help diagnose movement disorders. Imaging alone may not be enough for a definitive diagnosis, but it is often useful in clarifying clinical findings. These tests may include:

Magnetic Resonance Imaging (MRI) – Head: MRI can sometimes find problems in the brain that may be related to or cause a movement disorder, such as atrophy in certain parts of the brain.
Positron Emission Tomography (PET): Functional and neurochemical brain imaging with PET helps supply information on brain metabolism and chemistry.

How are movement disorders treated?

Watchful waiting may be best for some cases. Other cases may require more aggressive treatment. Your doctor may prescribe injections or medications such as:

beta blockers to reduce shaking and other physical symptoms.
anti-seizure medications to reduce tremors, especially in the hands.
anti-cholinergic agents to treat dystonia by reducing the effects of a brain chemical called acetylcholine. This may decrease tremors or muscle stiffness.
anti-anxiety medications to work on the central nervous system and relax the muscles to supply short-term relief from spasms.
botulinum toxin (Botox®) to block certain chemicals in the brain (neurotransmitters) that can cause muscle spasms.

If you have a movement disorder, Deep Brain Stimulation (DBS) may reduce your involuntary movements. A two-part procedure first implants a small electrode in the brain using general anesthesia. The second surgery connects a wire from the electrode to a small battery pack that sends electrical impulses by pushing a button. Once the electrode is in place, you can adjust the device on your own. You will work with a neurologist to determine the combination of settings that best control your symptoms.

Doctors are studying MR-guided Focused Ultrasound (MRgFUS) as a treatment for some movement disorders. The procedure uses focused beams of sound energy to heat and destroy a small volume of brain tissue without harming adjacent tissue.

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